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Induction of Unconventional T Cells by a Mutant Mycobacterium bovis BCG Strain Formulated in Cationic Liposomes Correlates with Protection against Mycobacterium tuberculosis Infections of Immunocompromised Mice

Earlier studies aimed at defining protective immunity induced by Mycobacterium bovis BCG immunization have largely focused on the induction of antituberculosis CD4(+) and CD8(+) T cell responses. Here we describe a vaccine consisting of a BCGΔmmaA4 deletion mutant formulated in dimethyl dioctadecyl-...

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Detalhes bibliográficos
Publicado no:Clin Vaccine Immunol
Main Authors: Derrick, Steven C., Yabe, Idalia, Morris, Sheldon, Cowley, Siobhan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933783/
https://ncbi.nlm.nih.gov/pubmed/27226281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00232-16
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