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Effective co-delivery of doxorubicin and dasatinib using a PEG-Fmoc nanocarrier for combination cancer chemotherapy
A simple PEGylated peptidic nanocarrier, PEG(5000)-lysyl-(α-Fmoc-ε-Cbz-lysine)(2) (PLFCL)(,) was developed for effective co-delivery of doxorubicin (DOX) and dasatinib (DAS) for combination chemotherapy. Significant synergy of DOX and DAS in inhibition of cancer cell proliferation was demonstrated i...
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| Publicado no: | Biomaterials |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4550547/ https://ncbi.nlm.nih.gov/pubmed/26210177 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2015.07.027 |
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