Musashi-2 Silencing Exerts Potent Activity against Acute Myeloid Leukemia and Enhances Chemosensitivity to Daunorubicin

RNA-binding protein Musashi-2 (Msi2) is known to play a critical role in leukemogenesis and contributes to poor clinical prognosis in acute myeloid leukemia (AML). However, the effect of Msi2 silencing on treatment for AML still remains poorly understood. In this study, we used lentivirus-mediated R...

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Publicado en:PLoS One
Main Authors: Han, Yixiang, Ye, Aifang, Zhang, Yan, Cai, Zhimin, Wang, Wei, Sun, Lan, Jiang, Songfu, Wu, Jianbo, Yu, Kang, Zhang, Shenghui
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2015
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4550418/
https://ncbi.nlm.nih.gov/pubmed/26308531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0136484
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