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Musashi-2 Silencing Exerts Potent Activity against Acute Myeloid Leukemia and Enhances Chemosensitivity to Daunorubicin

RNA-binding protein Musashi-2 (Msi2) is known to play a critical role in leukemogenesis and contributes to poor clinical prognosis in acute myeloid leukemia (AML). However, the effect of Msi2 silencing on treatment for AML still remains poorly understood. In this study, we used lentivirus-mediated R...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Han, Yixiang, Ye, Aifang, Zhang, Yan, Cai, Zhimin, Wang, Wei, Sun, Lan, Jiang, Songfu, Wu, Jianbo, Yu, Kang, Zhang, Shenghui
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4550418/
https://ncbi.nlm.nih.gov/pubmed/26308531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0136484
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