Acute Myeloid Leukemia Cells Express ICOS Ligand to Promote the Expansion of Regulatory T Cells

CD4(+)CD25(+)Foxp3(+) regulatory T cells (Tregs) accumulate in bone marrow microenvironment in acute myeloid leukemia (AML). However, little is known about how the tumor environment including tumor cells themselves affects this process. Here we demonstrated that AML cells expressed inducible T-cell...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Han, Yixiang, Dong, Yuqing, Yang, Qianqian, Xu, Wanling, Jiang, Songfu, Yu, Zhijie, Yu, Kang, Zhang, Shenghui
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6168677/
https://ncbi.nlm.nih.gov/pubmed/30319662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02227
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