Therapeutic implications of intratumor heterogeneity for TP53 mutational status in Burkitt lymphoma

Therapeutic implications of intra-tumor heterogeneity are still undefined. In this study we report a genetic and functional analysis aimed at defining the mechanisms of chemoresistance in a 43-year old woman affected by stage IVB Burkitt lymphoma with bulky abdominal masses and peritoneal effusion....

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Veröffentlicht in:Exp Hematol Oncol
Hauptverfasser: Derenzini, Enrico, Iacobucci, Ilaria, Agostinelli, Claudio, Imbrogno, Enrica, Storlazzi, Clelia Tiziana, L`Abbate, Alberto, Casadei, Beatrice, Ferrari, Anna, Di Rora`, Andrea Ghelli Luserna, Martinelli, Giovanni, Pileri, Stefano, Zinzani, Pier Luigi
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Case Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4549912/
https://ncbi.nlm.nih.gov/pubmed/26312160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40164-015-0019-9
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