Therapeutic implications of intratumor heterogeneity for TP53 mutational status in Burkitt lymphoma

Therapeutic implications of intra-tumor heterogeneity are still undefined. In this study we report a genetic and functional analysis aimed at defining the mechanisms of chemoresistance in a 43-year old woman affected by stage IVB Burkitt lymphoma with bulky abdominal masses and peritoneal effusion....

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Vydáno v:Exp Hematol Oncol
Hlavní autoři: Derenzini, Enrico, Iacobucci, Ilaria, Agostinelli, Claudio, Imbrogno, Enrica, Storlazzi, Clelia Tiziana, L`Abbate, Alberto, Casadei, Beatrice, Ferrari, Anna, Di Rora`, Andrea Ghelli Luserna, Martinelli, Giovanni, Pileri, Stefano, Zinzani, Pier Luigi
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
Témata:
Case Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4549912/
https://ncbi.nlm.nih.gov/pubmed/26312160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40164-015-0019-9
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