Phosphatase and tensin homolog (PTEN) in antigen-presenting cells controls Th17-mediated autoimmune arthritis

INTRODUCTION: Autoreactive T cells are a central element in many systemic autoimmune diseases. The generation of these pathogenic T cells is instructed by antigen-presenting cells (APCs). However, signaling pathways in APCs that drive autoimmune diseases, such as rheumatoid arthritis, are not unders...

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Vydáno v:Arthritis Res Ther
Hlavní autoři: Blüml, Stephan, Sahin, Emine, Saferding, Victoria, Goncalves-Alves, Eliana, Hainzl, Eva, Niederreiter, Birgit, Hladik, Anastasia, Lohmeyer, Tobias, Brunner, Julia S., Bonelli, Michael, Koenders, Marije I., van den Berg, Wim B., Superti-Furga, Giulio, Smolen, Josef S., Schabbauer, Gernot, Redlich, Kurt
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4549861/
https://ncbi.nlm.nih.gov/pubmed/26307404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-015-0742-y
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