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Macrophage PTEN Regulates Expression and Secretion of Arginase I Modulating Innate and Adaptive Immune Responses

The activation of innate immune cells triggers numerous intracellular signaling pathways, which require tight control to mount an adequate immune response. The PI3K signaling pathway is intricately involved in innate immunity, and its activation dampens the expression and release of proinflammatory...

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Detalhes bibliográficos
Main Authors: Sahin, Emine, Haubenwallner, Stefan, Kuttke, Mario, Kollmann, Isabella, Halfmann, Angela, Dohnal, Alexander B., Chen, Li, Cheng, Paul, Hoesel, Bastian, Einwallner, Elisa, Brunner, Julia, Kral, Julia B., Schrottmaier, Waltraud C., Thell, Kathrin, Saferding, Victoria, Blüml, Stephan, Schabbauer, Gernot
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4120896/
https://ncbi.nlm.nih.gov/pubmed/25015834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302167
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