Sustained PI3K Activation exacerbates BLM-induced Lung Fibrosis via activation of pro-inflammatory and pro-fibrotic pathways

Idiopathic pulmonary fibrosis (IPF) is a life-threatening disease with limited treatment options. Additionally, the lack of a complete understanding of underlying immunological mechanisms underscores the importance of discovering novel options for therapeutic intervention. Since the PI3K/PTEN pathwa...

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Publicado no:Sci Rep
Main Authors: Kral, Julia Barbara, Kuttke, Mario, Schrottmaier, Waltraud Cornelia, Birnecker, Birgit, Warszawska, Joanna, Wernig, Christina, Paar, Hannah, Salzmann, Manuel, Sahin, Emine, Brunner, Julia Stefanie, Österreicher, Christoph, Knapp, Sylvia, Assinger, Alice, Schabbauer, Gernot
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4789787/
https://ncbi.nlm.nih.gov/pubmed/26971883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23034
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