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Sustained PI3K Activation exacerbates BLM-induced Lung Fibrosis via activation of pro-inflammatory and pro-fibrotic pathways

Idiopathic pulmonary fibrosis (IPF) is a life-threatening disease with limited treatment options. Additionally, the lack of a complete understanding of underlying immunological mechanisms underscores the importance of discovering novel options for therapeutic intervention. Since the PI3K/PTEN pathwa...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Kral, Julia Barbara, Kuttke, Mario, Schrottmaier, Waltraud Cornelia, Birnecker, Birgit, Warszawska, Joanna, Wernig, Christina, Paar, Hannah, Salzmann, Manuel, Sahin, Emine, Brunner, Julia Stefanie, Österreicher, Christoph, Knapp, Sylvia, Assinger, Alice, Schabbauer, Gernot
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2016
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4789787/
https://ncbi.nlm.nih.gov/pubmed/26971883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23034
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