Sustained PI3K Activation exacerbates BLM-induced Lung Fibrosis via activation of pro-inflammatory and pro-fibrotic pathways

Idiopathic pulmonary fibrosis (IPF) is a life-threatening disease with limited treatment options. Additionally, the lack of a complete understanding of underlying immunological mechanisms underscores the importance of discovering novel options for therapeutic intervention. Since the PI3K/PTEN pathwa...

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Vydáno v:Sci Rep
Hlavní autoři: Kral, Julia Barbara, Kuttke, Mario, Schrottmaier, Waltraud Cornelia, Birnecker, Birgit, Warszawska, Joanna, Wernig, Christina, Paar, Hannah, Salzmann, Manuel, Sahin, Emine, Brunner, Julia Stefanie, Österreicher, Christoph, Knapp, Sylvia, Assinger, Alice, Schabbauer, Gernot
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4789787/
https://ncbi.nlm.nih.gov/pubmed/26971883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23034
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