Sustained PI3K Activation exacerbates BLM-induced Lung Fibrosis via activation of pro-inflammatory and pro-fibrotic pathways

Idiopathic pulmonary fibrosis (IPF) is a life-threatening disease with limited treatment options. Additionally, the lack of a complete understanding of underlying immunological mechanisms underscores the importance of discovering novel options for therapeutic intervention. Since the PI3K/PTEN pathwa...

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Publicado en:Sci Rep
Autores principales: Kral, Julia Barbara, Kuttke, Mario, Schrottmaier, Waltraud Cornelia, Birnecker, Birgit, Warszawska, Joanna, Wernig, Christina, Paar, Hannah, Salzmann, Manuel, Sahin, Emine, Brunner, Julia Stefanie, Österreicher, Christoph, Knapp, Sylvia, Assinger, Alice, Schabbauer, Gernot
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4789787/
https://ncbi.nlm.nih.gov/pubmed/26971883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23034
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