Macrophage PTEN Regulates Expression and Secretion of Arginase I Modulating Innate and Adaptive Immune Responses

The activation of innate immune cells triggers numerous intracellular signaling pathways, which require tight control to mount an adequate immune response. The PI3K signaling pathway is intricately involved in innate immunity, and its activation dampens the expression and release of proinflammatory...

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Main Authors: Sahin, Emine, Haubenwallner, Stefan, Kuttke, Mario, Kollmann, Isabella, Halfmann, Angela, Dohnal, Alexander B., Chen, Li, Cheng, Paul, Hoesel, Bastian, Einwallner, Elisa, Brunner, Julia, Kral, Julia B., Schrottmaier, Waltraud C., Thell, Kathrin, Saferding, Victoria, Blüml, Stephan, Schabbauer, Gernot
Format: Artigo
Jezik:Inglês
Izdano: AAI 2014
Teme:
Immune Regulation
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4120896/
https://ncbi.nlm.nih.gov/pubmed/25015834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302167
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