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Multifunctional facets of retrovirus integrase
The retrovirus integrase (IN) is responsible for integration of the reverse transcribed linear cDNA into the host DNA genome. First, IN cleaves a dinucleotide from the 3’ OH blunt ends of the viral DNA exposing the highly conserved CA sequence in the recessed ends. IN utilizes the 3’ OH ends to cata...
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| Publicado en: | World J Biol Chem |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Baishideng Publishing Group Inc
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4549773/ https://ncbi.nlm.nih.gov/pubmed/26322168 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4331/wjbc.v6.i3.83 |
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