The HIV-1 Integrase Monomer Induces a Specific Interaction with LTR DNA for Concerted Integration()

The assembly mechanism for the human immunodeficiency virus type-1 (HIV) synaptic complex (SC) capable of concerted integration is unknown. Molecular and structural studies have established that the HIV SC and prototype foamy virus (PFV) intasome contain a tetramer of integrase (IN) that catalyzes c...

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Bibliographic Details
Main Authors: Pandey, Krishan K., Bera, Sibes, Grandgenett, Duane P.
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3212032/
https://ncbi.nlm.nih.gov/pubmed/21992419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi201247f
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