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Distinct OGT-Binding Sites Promote HCF-1 Cleavage
Human HCF-1 (also referred to as HCFC-1) is a transcriptional co-regulator that undergoes a complex maturation process involving extensive O-GlcNAcylation and site-specific proteolysis. HCF-1 proteolysis results in two active, noncovalently associated HCF-1(N) and HCF-1(C) subunits that regulate dis...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4549301/ https://ncbi.nlm.nih.gov/pubmed/26305326 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0136636 |
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