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Morphine promotes astrocyte-preferential differentiation of mouse hippocampal progenitor cells via PKCε-dependent ERK activation and TRBP phosphorylation
Previously we have shown that morphine regulates adult neurogenesis by modulating miR-181a maturation and subsequent hippocampal neural progenitor cell (NPC) lineages. By using NPCs cultured from PKCε or β-arrestin2 knockout mice and the MEK inhibitor U0126, we demonstrate that regulation of NPC dif...
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| Publicado no: | Stem Cells |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4549172/ https://ncbi.nlm.nih.gov/pubmed/26012717 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.2055 |
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