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Morphine regulates adult neurogenesis and contextual memory extinction via the PKCε/Prox1 pathway

We have previously reported that the miR-181a/Prox1/Notch1 pathway mediates the effect of morphine on modulating lineage-specific differentiation of adult neural stem/progenitor cells (NSPCs) via a PKCε-dependent pathway, whereas fentanyl shows no such effect. However, the role of the PKCε/Prox1 pat...

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Bibliographische Detailangaben
Veröffentlicht in:Neuropharmacology
Hauptverfasser: Fan, Wenxiang, Wang, Helei, Zhang, Yue, Loh, Horace H., Law, Ping-Yee, Xu, Chi
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6338672/
https://ncbi.nlm.nih.gov/pubmed/30170081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2018.08.031
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