Morphine promotes astrocyte-preferential differentiation of mouse hippocampal progenitor cells via PKCε-dependent ERK activation and TRBP phosphorylation

Previously we have shown that morphine regulates adult neurogenesis by modulating miR-181a maturation and subsequent hippocampal neural progenitor cell (NPC) lineages. By using NPCs cultured from PKCε or β-arrestin2 knockout mice and the MEK inhibitor U0126, we demonstrate that regulation of NPC dif...

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Detaylı Bibliyografya
Yayımlandı:Stem Cells
Asıl Yazarlar: Xu, Chi, Zheng, Hui, Loh, Horace H., Law, Ping-Yee
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4549172/
https://ncbi.nlm.nih.gov/pubmed/26012717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.2055
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