Marked Disturbance of Calcium Homeostasis in Mice With Targeted Disruption of the Trpv6 Calcium Channel Gene

We report the phenotype of mice with targeted disruption of the Trpv6 (Trpv6 KO) epithelial calcium channel. The mice exhibit disordered Ca(2+) homeostasis, including defective intestinal Ca(2+) absorption, increased urinary Ca(2+) excretion, decreased BMD, deficient weight gain, and reduced fertili...

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Detalhes bibliográficos
Publicado no:J Bone Miner Res
Main Authors: Bianco, Suzy DC, Peng, Ji-Bin, Takanaga, Hitomi, Suzuki, Yoshiro, Crescenzi, Alessandra, Kos, Claudine H, Zhuang, Liyan, Freeman, Michael R, Gouveia, Cecilia HA, Wu, Jiangping, Luo, Hongyu, Mauro, Theodora, Brown, Edward M, Hediger, Matthias A
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4548943/
https://ncbi.nlm.nih.gov/pubmed/17129178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1359/jbmr.061110
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