Photoswitchable Inhibitor of the Calcium Channel TRPV6

[Image: see text] Herein we report the first photoswitchable inhibitor of Transient Receptor Potential Vanilloid 6 (TRPV6), a selective calcium channel involved in a number of diseases and in cancer progression. By surveying analogs of a previously reported TRPV6 inhibitor appended with a phenyl-dia...

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izdano v:ACS Med Chem Lett
Main Authors: Cunha, Micael R., Bhardwaj, Rajesh, Lindinger, Sonja, Butorac, Carmen, Romanin, Christoph, Hediger, Matthias A., Reymond, Jean-Louis
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2019
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6746075/
https://ncbi.nlm.nih.gov/pubmed/31531207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.9b00298
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