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The calcium-sensing receptor is required for normal calcium homeostasis independent of parathyroid hormone

The extracellular calcium-sensing receptor (CaR; alternate gene names, CaR or Casr) is a membrane-spanning G protein–coupled receptor. CaR is highly expressed in the parathyroid gland, and is activated by extracellular calcium (Ca(2+)(o)). Mice homozygous for null mutations in the CaR gene (CaR(–/–)...

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Главные авторы: Kos, Claudine H., Karaplis, Andrew C., Peng, Ji-Bin, Hediger, Matthias A., Goltzman, David, Mohammad, Khalid S., Guise, Theresa A., Pollak, Martin R.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 2003
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC152589/
https://ncbi.nlm.nih.gov/pubmed/12671051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200317416
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