Leukemia stem cells in T-ALL require active Hif1α and Wnt signaling

The Wnt signaling pathway has been shown to play important roles in normal hematopoietic stem cell biology and in the development of both acute and chronic myelogenous leukemia. Its role in maintaining established leukemia stem cells, which are more directly relevant to patients with disease, howeve...

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Bibliographische Detailangaben
Veröffentlicht in:Blood
Hauptverfasser: Giambra, Vincenzo, Jenkins, Catherine E., Lam, Sonya H., Hoofd, Catherine, Belmonte, Miriam, Wang, Xuehai, Gusscott, Sam, Gracias, Deanne, Weng, Andrew P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2015
Schlagworte:
Lymphoid Neoplasia
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4548498/
https://ncbi.nlm.nih.gov/pubmed/25934477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-10-609370
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