Leukemia stem cells in T-ALL require active Hif1α and Wnt signaling

The Wnt signaling pathway has been shown to play important roles in normal hematopoietic stem cell biology and in the development of both acute and chronic myelogenous leukemia. Its role in maintaining established leukemia stem cells, which are more directly relevant to patients with disease, howeve...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Giambra, Vincenzo, Jenkins, Catherine E., Lam, Sonya H., Hoofd, Catherine, Belmonte, Miriam, Wang, Xuehai, Gusscott, Sam, Gracias, Deanne, Weng, Andrew P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2015
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4548498/
https://ncbi.nlm.nih.gov/pubmed/25934477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-10-609370
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