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The Discovery and Development of Boceprevir: A Novel, First-generation Inhibitor of the Hepatitis C Virus NS3/4A Serine Protease

An estimated 2–3% of the world's population is infected with hepatitis C virus (HCV), making it a major global health problem. Consequently, over the past 15 years, there has been a concerted effort to understand the pathophysiology of HCV infection and the molecular virology of replication, an...

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Detalhes bibliográficos
Publicado no:J Clin Transl Hepatol
Main Authors: Howe, Anita Y. M., Venkatraman, Srikanth
Formato: Artigo
Idioma:Inglês
Publicado em: XIA & HE Publishing Ltd 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4548358/
https://ncbi.nlm.nih.gov/pubmed/26357603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14218/JCTH.2013.002XX
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