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The role of Fc–FcγR interactions in IgG-mediated microbial neutralization
Antibodies are bifunctional molecules, containing a variable Fab domain that mediates binding specificity and a constant Fc domain that bridges antibody-coated targets with FcγR-expressing cells that mediate effector functions. Although traditional mechanisms of antibody-mediated neutralization of m...
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| 出版年: | J Exp Med |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Rockefeller University Press
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4548051/ https://ncbi.nlm.nih.gov/pubmed/26282878 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20151267 |
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