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Anesthetic and pathological changes following high doses of ketamine and xylazine in Sprague Dawley rats

The main objective of this study was to compare the effects of ketamine and xylazine in aging rats when coadministered intraperitoneally at high anesthetic doses. Three groups (n=6 rats/group) consisting of rats at 3, 6 and 12 months of age were used. During anesthesia, animals were monitored for he...

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Bibliografische gegevens
Gepubliceerd in:Exp Anim
Hoofdauteurs: GIROUX, Marie-Chantal, HÉLIE, Pierre, BURNS, Patrick, VACHON, Pascal
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Japanese Association for Laboratory Animal Science 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4547998/
https://ncbi.nlm.nih.gov/pubmed/25818316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1538/expanim.14-0088
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