Protein Tyrosine Phosphatase PTPRS Is an Inhibitory Receptor on Human and Murine Plasmacytoid Dendritic Cells

Plasmacytoid dendritic cells (pDCs) are primary producers of type I interferon (IFN) in response to viruses. The IFN-producing capacity of pDCs is regulated by specific inhibitory receptors, yet none of the known receptors are conserved in evolution. We report that within the human immune system, re...

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發表在:Immunity
Main Authors: Bunin, Anna, Sisirak, Vanja, Ghosh, Hiyaa S., Grajkowska, Lucja T., Hou, Z. Esther, Miron, Michelle, Yang, Cliff, Ceribelli, Michele, Uetani, Noriko, Chaperot, Laurence, Plumas, Joel, Hendriks, Wiljan, Tremblay, Michel L., Haecker, Hans, Staudt, Louis M., Green, Peter H., Bhagat, Govind, Reizis, Boris
格式: Artigo
語言:Inglês
出版: 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4547994/
https://ncbi.nlm.nih.gov/pubmed/26231120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2015.07.009
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