Isoform-specific expression and feedback regulation of E protein TCF4 control dendritic cell lineage specification

The cell fate decision between interferon-producing plasmacytoid DC (pDC) and antigen-presenting classical DC (cDC) is controlled by the E protein transcription factor TCF4 (E2-2). We report that TCF4 comprises two transcriptional isoforms, both of which are required for optimal pDC development in v...

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Detaylı Bibliyografya
Yayımlandı:Immunity
Asıl Yazarlar: Grajkowska, Lucja T., Ceribelli, Michele, Lau, Colleen M., Warren, Margaret E., Tiniakou, Ioanna, Higa, Sandra Nakandakari, Bunin, Anna, Haecker, Hans, Mirny, Leonid A., Staudt, Louis M., Reizis, Boris
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5243153/
https://ncbi.nlm.nih.gov/pubmed/27986456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2016.11.006
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