Plasmacytoid Dendritic Cells Are Largely Dispensable for the Pathogenesis of Experimental Inflammatory Bowel Disease

Inflammatory bowel disease (IBD) is a chronic inflammatory condition caused by an aberrant immune response to microbial components of the gastrointestinal tract. Plasmacytoid dendritic cells (pDCs) are innate immune cells specialized in the production of type I interferons and were recently implicat...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Catherine M. Sawai, Lee Serpas, Antonio Galvao Neto, Geunhyo Jang, Ali Rashidfarrokhi, Roland Kolbeck, Miguel A. Sanjuan, Boris Reizis, Vanja Sisirak
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2018-10-01
Schriftenreihe:Frontiers in Immunology
Schlagworte:
Plasmacytoid dendritic cell (PDC)
Interferon Type I
colitis
Inflammatory bowel disease (IBD)
autoimmune disease
Online Zugang:https://www.frontiersin.org/article/10.3389/fimmu.2018.02475/full
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