Protein Tyrosine Phosphatase PTPRS Is an Inhibitory Receptor on Human and Murine Plasmacytoid Dendritic Cells

Plasmacytoid dendritic cells (pDCs) are primary producers of type I interferon (IFN) in response to viruses. The IFN-producing capacity of pDCs is regulated by specific inhibitory receptors, yet none of the known receptors are conserved in evolution. We report that within the human immune system, re...

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Publicado en:Immunity
Main Authors: Bunin, Anna, Sisirak, Vanja, Ghosh, Hiyaa S., Grajkowska, Lucja T., Hou, Z. Esther, Miron, Michelle, Yang, Cliff, Ceribelli, Michele, Uetani, Noriko, Chaperot, Laurence, Plumas, Joel, Hendriks, Wiljan, Tremblay, Michel L., Haecker, Hans, Staudt, Louis M., Green, Peter H., Bhagat, Govind, Reizis, Boris
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4547994/
https://ncbi.nlm.nih.gov/pubmed/26231120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2015.07.009
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