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mTOR signaling in mice with dysfunctional cardiac ryanodine receptor ion channel
Simultaneous substitution of three amino acid residues in the calmodulin binding domain (W3587A/L3591D/F3603A, ADA) of the cardiac ryanodine receptor ion channel (RyR2) impairs calmodulin inhibition of RyR2 and causes cardiac hypertrophy and early death of Ryr2(ADA/ADA) mice. To determine the physio...
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| Izdano u: | J Receptor Ligand Channel Res |
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| Glavni autori: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2015
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4547478/ https://ncbi.nlm.nih.gov/pubmed/26312014 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JRLCR.S78410 |
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