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A Caged Ret Kinase Inhibitor and its Effect on Motoneuron Development in Zebrafish Embryos

Proto-oncogene tyrosine-protein kinase receptor RET is implicated in the development and maintenance of neurons of the central and peripheral nervous systems. Attaching activity-compromising photocleavable groups (caging) to inhibitors could allow for external spatiotemporally controlled inhibition...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Bliman, David, Nilsson, Jesper R., Kettunen, Petronella, Andréasson, Joakim, Grøtli, Morten
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4547397/
https://ncbi.nlm.nih.gov/pubmed/26300345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13109
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