8-Triazolylpurines: Towards Fluorescent Inhibitors of the MDM2/p53 Interaction

Small molecule nonpeptidic mimics of α-helices are widely recognised as protein-protein interaction (PPIs) inhibitors. Protein-protein interactions mediate virtually all important regulatory pathways in a cell, and the ability to control and modulate PPIs is therefore of great significance to basic...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS One
Egile Nagusiak: Pettersson, Mariell, Bliman, David, Jacobsson, Jimmy, Nilsson, Jesper R., Min, Jaeki, Iconaru, Luigi, Guy, R. Kiplin, Kriwacki, Richard W., Andréasson, Joakim, Grøtli, Morten
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2015
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4420247/
https://ncbi.nlm.nih.gov/pubmed/25942498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0124423
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