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NMR Dynamics of Transmembrane and Intracellular Domains of p75NTR in Lipid-Protein Nanodiscs

P75NTR is a type I integral membrane protein that plays a key role in neurotrophin signaling. However, structural data for the receptor in various functional states are sparse and controversial. In this work, we studied the spatial structure and mobility of the transmembrane and intracellular parts...

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Détails bibliographiques
Publié dans:Biophys J
Auteurs principaux: Mineev, Konstantin S., Goncharuk, Sergey A., Kuzmichev, Pavel K., Vilar, Marçal, Arseniev, Alexander S.
Format: Artigo
Langue:Inglês
Publié: The Biophysical Society 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4547337/
https://ncbi.nlm.nih.gov/pubmed/26287629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.07.009
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