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Revising the mechanism of p75NTR activation: intrinsically monomeric state of death domains invokes the "helper" hypothesis

The neurotrophin receptor p75NTR plays crucial roles in neuron development and regulates important neuronal processes like degeneration, apoptosis and cell survival. At the same time the detailed mechanism of signal transduction is unclear. One of the main hypotheses known as the snail-tong mechanis...

詳細記述

保存先:
書誌詳細
出版年:Sci Rep
主要な著者: Goncharuk, Sergey A., Artemieva, Lilya E., Nadezhdin, Kirill D., Arseniev, Alexander S., Mineev, Konstantin S.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7427093/
https://ncbi.nlm.nih.gov/pubmed/32792564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-70721-8
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