Prophylactic and postexposure efficacy of a potent human monoclonal antibody against MERS coronavirus

Middle East Respiratory Syndrome (MERS) is a highly lethal pulmonary infection caused by a previously unidentified coronavirus (CoV), likely transmitted to humans by infected camels. There is no licensed vaccine or antiviral for MERS, therefore new prophylactic and therapeutic strategies to combat h...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Corti, Davide, Zhao, Jincun, Pedotti, Mattia, Simonelli, Luca, Agnihothram, Sudhakar, Fett, Craig, Fernandez-Rodriguez, Blanca, Foglierini, Mathilde, Agatic, Gloria, Vanzetta, Fabrizia, Gopal, Robin, Langrish, Christopher J., Barrett, Nicholas A, Sallusto, Federica, Baric, Ralph S., Varani, Luca, Zambon, Maria, Perlman, Stanley, Lanzavecchia, Antonio
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2015
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4547275/
https://ncbi.nlm.nih.gov/pubmed/26216974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1510199112
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