Truncation of the human EGF receptor leads to differential transforming potentials in primary avian fibroblasts and erythroblasts.

The transforming capacity of the normal and mutant human EGF receptor (EGFR) was investigated in primary chicken cells. In fibroblasts, both N- and C-terminal truncations resulted in a weak, additive oncogenic activity. However, not even double truncations caused a v-erbB-like phenotype. Upon EGF-bi...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Khazaie, K, Dull, T J, Graf, T, Schlessinger, J, Ullrich, A, Beug, H, Vennström, B
Format: Artigo
Jezik:Inglês
Izdano: 1988
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC454693/
https://ncbi.nlm.nih.gov/pubmed/3263272
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki