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Transformation of mammalian fibroblasts and macrophages in vitro by a murine retrovirus encoding an avian v-myc oncogene.

A murine retrovirus which expresses the avain v-myc OK10 oncogene was constructed. The virus, denoted MMCV, readily transforms fibroblasts of established lines, such as mouse NIH/3T3 and rat 208F cells, to anchorage-independent growth in agarose. The virus also transforms primary mouse cells: (i) vi...

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Bibliographic Details
Main Authors: Vennström, B, Kahn, P, Adkins, B, Enrietto, P, Hayman, M J, Graf, T, Luciw, P
Format: Artigo
Language:Inglês
Published: 1984
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC557841/
https://ncbi.nlm.nih.gov/pubmed/6526015
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