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Carboxy-terminal truncations of epidermal growth factor (EGF) receptor affect diverse EGF-induced cellular responses.

The binding of epidermal growth factor (EGF) to its receptor induces tyrosine phosphorylation of phospholipase C gamma (PLC gamma), which appears to be necessary for its activation leading to phosphatidyl inositol (PI) hydrolysis. Moreover, EGF-receptor (EGF-R) activation and autophosphorylation res...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Cell Regul
Hauptverfasser: Li, W, Hack, N, Margolis, B, Ullrich, A, Skorecki, K, Schlessinger, J
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Cell Biology 1991
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC361854/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1777506/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.2.8.641
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