Carboxy-terminal truncations of epidermal growth factor (EGF) receptor affect diverse EGF-induced cellular responses.

The binding of epidermal growth factor (EGF) to its receptor induces tyrosine phosphorylation of phospholipase C gamma (PLC gamma), which appears to be necessary for its activation leading to phosphatidyl inositol (PI) hydrolysis. Moreover, EGF-receptor (EGF-R) activation and autophosphorylation res...

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Bibliografiske detaljer

Udgivet i:	Cell Regul
Principais autores:	Li, W, Hack, N, Margolis, B, Ullrich, A, Skorecki, K, Schlessinger, J
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Cell Biology 1991
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC361854/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1777506/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.2.8.641
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