An Inhibitory Role for the Transcription Factor Stat3 in Controlling IL-4 and Bcl6 Expression in Follicular Helper T cells

The transcription factor Bcl6 is required for the development of the follicular helper T (T(FH)) cells. Cytokines that activate Stat3 promote Bcl6 expression and T(FH) cell differentiation. Previous studies with an acute virus infection model showed that T(FH) cell differentiation was decreased but...

Full description

Saved in:
Bibliographic Details
Published in:J Immunol
Main Authors: Wu, Hao, Xu, Lin-Lin, Teuscher, Paulla, Liu, Hong, Kaplan, Mark H., Dent, Alexander L.
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546859/
https://ncbi.nlm.nih.gov/pubmed/26188063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500335
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items