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An Inhibitory Role for the Transcription Factor Stat3 in Controlling IL-4 and Bcl6 Expression in Follicular Helper T cells

The transcription factor Bcl6 is required for the development of the follicular helper T (T(FH)) cells. Cytokines that activate Stat3 promote Bcl6 expression and T(FH) cell differentiation. Previous studies with an acute virus infection model showed that T(FH) cell differentiation was decreased but...

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書目詳細資料
發表在:J Immunol
Main Authors: Wu, Hao, Xu, Lin-Lin, Teuscher, Paulla, Liu, Hong, Kaplan, Mark H., Dent, Alexander L.
格式: Artigo
語言:Inglês
出版: 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546859/
https://ncbi.nlm.nih.gov/pubmed/26188063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500335
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