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YAP1 Exerts Its Transcriptional Control via TEAD-Mediated Activation of Enhancers
YAP1 is a major effector of the Hippo pathway and a well-established oncogene. Elevated YAP1 activity due to mutations in Hippo pathway components or YAP1 amplification is observed in several types of human cancers. Here we investigated its genomic binding landscape in YAP1-activated cancer cells, a...
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| Wydane w: | PLoS Genet |
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| Główni autorzy: | , , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Public Library of Science
2015
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4546604/ https://ncbi.nlm.nih.gov/pubmed/26295846 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005465 |
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