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Effect of the acylation of TEAD4 on its interaction with co‐activators YAP and TAZ

The Hippo pathway is deregulated in various cancers, and the discovery of molecules that modulate this pathway may open new therapeutic avenues in oncology. TEA/ATTS domain (TEAD) transcription factors are the most distal elements of the Hippo pathway and their transcriptional activity is regulated...

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Detalhes bibliográficos
Publicado no:Protein Sci
Main Authors: Mesrouze, Yannick, Meyerhofer, Marco, Bokhovchuk, Fedir, Fontana, Patrizia, Zimmermann, Catherine, Martin, Typhaine, Delaunay, Clara, Izaac, Aude, Kallen, Joerg, Schmelzle, Tobias, Erdmann, Dirk, Chène, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5699492/
https://ncbi.nlm.nih.gov/pubmed/28960584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3312
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