Combined inhibition of Bcl-2/Bcl-xL and Usp9X/Bag3 overcomes apoptotic resistance in glioblastoma in vitro and in vivo

Despite great efforts taken to advance therapeutic measures for patients with glioblastoma, the clinical prognosis remains grim. The antiapoptotic Bcl-2 family protein Mcl-1 is overexpressed in glioblastoma and represents an important resistance factor to the BH-3 mimetic ABT263. In this study, we s...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Oncotarget
Egile Nagusiak: Karpel-Massler, Georg, Shu, Chang, Chau, Lily, Banu, Matei, Halatsch, Marc-Eric, Westhoff, Mike-Andrew, Ramirez, Yulian, Ross, Alonzo H., Bruce, Jeffrey N., Canoll, Peter, Siegelin, Markus D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Impact Journals LLC 2015
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546483/
https://ncbi.nlm.nih.gov/pubmed/26008975
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