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Endothelial Cell mTOR Complex-2 Regulates Sprouting Angiogenesis

Tumor neovascularization is targeted by inhibition of vascular endothelial growth factor (VEGF) or the receptor to prevent tumor growth, but drug resistance to angiogenesis inhibition limits clinical efficacy. Inhibition of the phosphoinositide 3 kinase pathway intermediate, mammalian target of rapa...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Farhan, Maikel A., Carmine-Simmen, Katia, Lewis, John D., Moore, Ronald B., Murray, Allan G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546419/
https://ncbi.nlm.nih.gov/pubmed/26295809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135245
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