Comparative Analysis of Two Gene-Targeting Approaches Challenges the Tumor-Suppressive Role of the Protein Kinase MK5/PRAK

MK5 (MAPK-activated protein kinase 5) or PRAK (p38-regulated and -activated kinase) are alternative names for a serine/threonine protein kinase downstream to ERK3/4 and p38 MAPK. A previous gene targeting approach for MK5/PRAK (termed here MK5/PRAK-Δex8) revealed a seemingly tumor-suppressive role o...

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發表在:PLoS One
Main Authors: Ronkina, Natalia, Johansen, Claus, Bohlmann, Lisa, Lafera, Juri, Menon, Manoj B., Tiedje, Christopher, Laaß, Kathrin, Turk, Benjamin E., Iversen, Lars, Kotlyarov, Alexey, Gaestel, Matthias
格式: Artigo
語言:Inglês
出版: Public Library of Science 2015
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546416/
https://ncbi.nlm.nih.gov/pubmed/26295581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0136138
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