Elimination of Protein Kinase MK5/PRAK Activity by Targeted Homologous Recombination

MK5 (mitogen-activated protein kinase [MAPK]-activated protein kinase 5), also designated PRAK (p38-regulated and -activated kinase), was deleted from mice by homologous recombination. Although no MK5 full-length protein and kinase activity was detected in the MK5 knockout mice, the animals were via...

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Detalhes bibliográficos
Main Authors: Shi, Yu, Kotlyarov, Alexey, Laaß, Kathrin, Gruber, Achim D., Butt, Elke, Marcus, Katrin, Meyer, Helmut E., Friedrich, Anke, Volk, Hans-Dieter, Gaestel, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC207624/
https://ncbi.nlm.nih.gov/pubmed/14560018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.21.7732-7741.2003
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