Purα Is Essential for Postnatal Brain Development and Developmentally Coupled Cellular Proliferation As Revealed by Genetic Inactivation in the Mouse

The single-stranded DNA- and RNA-binding protein, Purα, has been implicated in many biological processes, including control of transcription of multiple genes, initiation of DNA replication, and RNA transport and translation. Deletions of the PURA gene are frequent in acute myeloid leukemia. Mice wi...

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Autores principales: Khalili, Kamel, Del Valle, Luis, Muralidharan, Vandhana, Gault, William J., Darbinian, Nune, Otte, Jessica, Meier, Ellen, Johnson, Edward M., Daniel, Dianne C., Kinoshita, Yayoi, Amini, Shohreh, Gordon, Jennifer
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2003
Materias:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC193944/
https://ncbi.nlm.nih.gov/pubmed/12972605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.19.6857-6875.2003
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