let-7b suppresses apoptosis and autophagy of human mesenchymal stem cells transplanted into ischemia/reperfusion injured heart 7by targeting caspase-3

INTRODUCTION: Mesenchymal stem cells (MSCs) have therapeutic potential for the repair of myocardial injury. The efficacy of MSC therapy for myocardial regeneration mainly depends on the survival of cells after transplantation into the infarcted heart. In the transplanted regions, reactive oxygen spe...

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Bibliografiske detaljer
Udgivet i:Stem Cell Res Ther
Main Authors: Ham, Onju, Lee, Se-Yeon, Lee, Chang Youn, Park, Jun-Hee, Lee, Jiyun, Seo, Hyang-Hee, Cha, Min-Ji, Choi, Eunhyun, Kim, Soonhag, Hwang, Ki-Chul
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546263/
https://ncbi.nlm.nih.gov/pubmed/26296645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-015-0134-x
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